Bioinks for Biofabrication: Current State and Future Perspectives
Figure from Wake Forest University.
Recent progress in 3D printing technologies is leading a revolution in cell culture methods. These systems design complex physiologically relevant 3D environments. 3D culture technologies rely heavily on bioinks, the raw cells and biomaterials used to create these 3D cultures. These bioinks, ranging from cell suspensions to hard acellular thermoplastics, must function with 3D systems and offer biocompatible environments that mimic in vivo tissue characteristics. While much progress has been made, for the production of increasingly complex reproducible 3D tissues a full biofabrication platform with both improved technology and superior bioinks must be developed. This Regmednet article reviews developed bioinks and important properties for these materials, reccent advances in bioinks and future considerations for 3D biofabrication.